The role of the superficial region in determining the dynamic properties of articular 1 cartilage 2 3

نویسندگان

  • Alanna R. Gannon
  • Thomas Nagel
  • Daniel J. Kelly
  • Daniel Kelly
چکیده

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

The changing role of the superficial region in determining the dynamic compressive properties of articular cartilage during postnatal development.

OBJECTIVE To explore how changes to the superficial region (SR) of articular cartilage during skeletal development impact its functional properties. It was hypothesised that a functional superficial region is not present in skeletally immature articular cartilage, and removal of this zone of the tissue would only negatively impact the dynamic modulus of the tissue with the attainment of skeleta...

متن کامل

Experimental Study on Protective Role of NSAID on Articular Cartilage Destruction in Septic Arthritis

Background: Surgical drainage and antibiotic therapy are the cornerstones of treatment protocols in septic arthritis; however, in some circumstances, the diagnosis and initiation of treatment may be retarded by slow disease progression or the time when the patient’s condition precludes early surgery. Therefore, it is beneficial to find ways to reduce the amount of articular injury. This study a...

متن کامل

Depth-Dependent Anisotropy of the Micromechanical Properties of Porcine Articular Cartilage Measured via Atomic Force Microscopy

INTRODUCTION: Articular cartilage exhibits distinct differences in biochemical composition [1] and structure [2] of the extracellular matrix (ECM) with distance from the articular surface. These differences result in depth-dependent biomechanical properties [3, 4, 5] that can have a significant effect on the mechanical environment of the chondrocyte [6, 7]. An additional structural component of...

متن کامل

CD147 (Extracellular Matrix Metalloproteinase Inducer-EMMPRIN) Expression by Human Articular Chondrocytes

Background: Integrins are a family of transmembrane proteins that allow communication between the extracellular matrix and the interior of cells. Chondrocytes, cells of articular cartilage, express integrins and these molecules appear to have a variety of roles including mechanotransduction. Integrins are known to associate with a number of accessory molecules such as CD147 that may act to regu...

متن کامل

The Effect of Mesenchymal Stem Cells and Aqueous Extract of Elaeagnus Angustifolia on the Mechanical Properties of Articular Cartilage in an Experimental Model of Rat Osteoarthritis

Introduction: Although, the effect of direct intra-articular injection of bone marrow stem cells (BMSCs) on the repair of articular cartilage and the effect of Elaeagnus angustifolia extract on pain relief in patients with osteoarthritis have been investigated, no studies has been conducted to compare the effects of these two therapeutic methods on the mechanical properties of articular cartila...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:

دوره   شماره 

صفحات  -

تاریخ انتشار 2012